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Lawrence Blonde Selected Research

Glucagon-Like Peptide-1 Receptor

1/2021Switching to iGlarLixi versus continuation of a daily or weekly glucagon-like peptide-1 receptor agonist (GLP-1 RA) in insufficiently controlled type 2 diabetes: A LixiLan-G trial subgroup analysis by HbA1c and GLP-1 RA use at screening.
1/2021Durable Effects of iGlarLixi Up to 52 Weeks in Type 2 Diabetes: The LixiLan-G Extension Study.
11/2020Efficacy and safety of iGlarLixi versus IDegLira in adults with type 2 diabetes inadequately controlled by glucagon-like peptide-1 receptor agonists: a systematic literature review and indirect treatment comparison.
1/2020Impact of disease duration and β-cell reserve on the efficacy of switching to iGlarLixi in adults with type 2 diabetes on glucagon-like peptide-1 receptor agonist therapy: Exploratory analyses from the LixiLan-G trial.
11/2019Switching to iGlarLixi Versus Continuing Daily or Weekly GLP-1 RA in Type 2 Diabetes Inadequately Controlled by GLP-1 RA and Oral Antihyperglycemic Therapy: The LixiLan-G Randomized Clinical Trial.
1/2019Clinical Characteristics and Glycemic Outcomes of Patients with Type 2 Diabetes Requiring Maximum Dose Insulin Glargine/Lixisenatide Fixed-Ratio Combination or Insulin Glargine in the LixiLan-L Trial.
1/2019Rationale for a titratable fixed-ratio co-formulation of a basal insulin analog and a glucagon-like peptide 1 receptor agonist in patients with type 2 diabetes.
8/2018GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONISTS FOR TYPE 2 DIABETES: A COMPREHENSIVE REVIEW OF HOW TO WEIGH THE OPTIONS, SELECT THE RIGHT PATIENTS, AND MAXIMIZE BENEFITS.
1/2017Lixisenatide as add-on treatment among patients with different β-cell function levels as assessed by HOMA-β index.
5/2015Once-weekly dulaglutide versus bedtime insulin glargine, both in combination with prandial insulin lispro, in patients with type 2 diabetes (AWARD-4): a randomised, open-label, phase 3, non-inferiority study.
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Lawrence Blonde Research Topics

Disease

86Type 2 Diabetes Mellitus (MODY)
05/2023 - 01/2002
25Hypoglycemia (Reactive Hypoglycemia)
10/2022 - 04/2004
15Body Weight (Weight, Body)
10/2022 - 05/2008
12Weight Loss (Weight Reduction)
05/2023 - 11/2006
11Weight Gain
01/2021 - 12/2004
8Cardiovascular Diseases (Cardiovascular Disease)
05/2023 - 10/2012
6Hypertension (High Blood Pressure)
05/2023 - 08/2005
6Dyslipidemias (Dyslipidemia)
05/2023 - 08/2005
5Heart Failure
01/2022 - 10/2012
5Nausea
11/2020 - 07/2009
5Diabetes Complications
01/2012 - 10/2002
5Hyperglycemia
03/2010 - 04/2003
4Diabetes Mellitus
05/2023 - 11/2006
4Insulin Resistance
10/2021 - 10/2002
3Prediabetic State (Prediabetes)
05/2023 - 11/2011
3Type 1 Diabetes Mellitus (Autoimmune Diabetes)
10/2022 - 12/2004
2Obesity
05/2023 - 10/2022
2Overweight
05/2023 - 11/2006
2Kidney Diseases (Kidney Disease)
10/2022 - 01/2022
2Neoplasms (Cancer)
10/2022 - 11/2013
2Body Weight Changes
11/2020 - 01/2020
2Vomiting
11/2019 - 05/2015
2Stroke (Strokes)
01/2015 - 10/2012
2Metabolic Diseases (Metabolic Disease)
01/2015 - 11/2006
2Myocardial Infarction
01/2015 - 10/2012
1Infertility (Sterility)
10/2022
1Diabetic Neuropathies (Diabetic Neuropathy)
10/2022
1Cardiogenic Shock
05/2015
1Pneumonia (Pneumonitis)
05/2015
1Ventricular Fibrillation
05/2015
1Fibrosis (Cirrhosis)
10/2014
1Chronic Renal Insufficiency
10/2014
1Sepsis (Septicemia)
10/2014
1Unstable Angina
10/2012

Drug/Important Bio-Agent (IBA)

41Insulin (Novolin)FDA Link
05/2023 - 10/2004
23Glucose (Dextrose)FDA LinkGeneric
05/2023 - 10/2002
22Hypoglycemic Agents (Hypoglycemics)IBA
05/2023 - 04/2004
16Insulin Glargine (Lantus)FDA Link
01/2022 - 04/2013
15Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
10/2022 - 10/2002
14Glucagon-Like Peptide 1 (GLP 1)IBA
10/2022 - 02/2009
13Glucagon-Like Peptide-1 ReceptorIBA
01/2021 - 07/2009
12LiraglutideFDA Link
10/2021 - 02/2009
11CanagliflozinIBA
01/2021 - 01/2014
11Metformin (Glucophage)FDA LinkGeneric
01/2021 - 04/2004
9SodiumIBA
01/2022 - 05/2014
9Blood Glucose (Blood Sugar)IBA
11/2020 - 01/2002
8lixisenatideIBA
01/2022 - 01/2017
7Glucagon-Like Peptide-1 Receptor AgonistsIBA
01/2022 - 12/2009
6Exenatide (Byetta)FDA Link
11/2019 - 07/2009
6LipidsIBA
08/2018 - 01/2005
5SymportersIBA
01/2021 - 04/2015
5Sitagliptin Phosphate (Januvia)FDA Link
11/2020 - 01/2013
4Hemoglobins (Hemoglobin)IBA
06/2021 - 11/2008
4insulin degludecIBA
01/2021 - 04/2013
4glimepiride (Amarel)FDA LinkGeneric
05/2016 - 02/2009
4oxidized low density lipoproteinIBA
11/2015 - 01/2014
4Bromocriptine (Parlodel)FDA LinkGeneric
01/2015 - 11/2011
3Sodium-Glucose Transporter 2 InhibitorsIBA
01/2021 - 05/2014
3dulaglutideIBA
11/2019 - 05/2015
3InsulinsIBA
11/2019 - 05/2014
3LDL CholesterolIBA
11/2015 - 01/2014
3Insulin Lispro (Humalog)FDA Link
05/2015 - 05/2014
3IncretinsIBA
11/2011 - 09/2006
2semaglutideIBA
10/2022 - 11/2020
2empagliflozinIBA
01/2021 - 11/2020
2dapagliflozinIBA
01/2021 - 01/2018
2IDegLiraIBA
11/2020 - 04/2016
2rGLP-1 proteinIBA
11/2019 - 01/2017
2Sodium-Glucose Transport ProteinsIBA
11/2019 - 01/2014
2ThiazolidinedionesIBA
01/2018 - 10/2002
2CholesterolIBA
02/2015 - 01/2012
2Triglycerides (Triacylglycerol)IBA
02/2015 - 01/2013
2Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
01/2015 - 10/2012
2Protamines (Protamine Sulfate)FDA Link
05/2014 - 05/2014
2Nonesterified Fatty Acids (NEFA)IBA
01/2013 - 11/2006
2Rosiglitazone (Avandia)FDA Link
07/2009 - 02/2009
1VaccinesIBA
05/2023
1Peptides (Polypeptides)IBA
10/2022
1CreatinineIBA
06/2021
1Pioglitazone (Actos)FDA Link
11/2019
1omega-Chloroacetophenone (Mace)IBA
08/2018
1Insulin Detemir (Levemir)FDA Link
01/2018
1Urea (Carbamide)FDA LinkGeneric
01/2016
1HDL CholesterolIBA
11/2015
1EnzymesIBA
02/2015
1SympatholyticsIBA
01/2015
1ORALIT (ORS)IBA
10/2014
1Dipeptidyl-Peptidases and Tripeptidyl-PeptidasesIBA
05/2014
1Glucagon-Like Peptides (Enteroglucagon)IBA
05/2014
1Isophane Insulin (NPH Insulin)FDA Link
05/2014
1Dipeptidyl-Peptidase IV InhibitorsIBA
05/2014
1Human Isophane InsulinFDA Link
11/2013
1SecretagoguesIBA
11/2011

Therapy/Procedure

37Therapeutics
10/2022 - 10/2002
25Glycemic Control
05/2023 - 01/2002
4Injections
11/2020 - 10/2004
3Drug Therapy (Chemotherapy)
10/2022 - 03/2010
2Nutrition Therapy (Medical Nutrition Therapy)
03/2010 - 11/2006
1Bariatric Surgery
10/2022
1Length of Stay
10/2014